Opportunistic nature of the mammalian microsporidia: experimental transmission of Trachipleistophora extenrec (Fungi: Microsporidia) between mammalian and insect hosts

0364796 - BC 2012 RIV DE eng J - Journal Article
Vávra, Jiří - Kamler, M. - Modrý, David - Koudela, Břetislav
Opportunistic nature of the mammalian microsporidia: experimental transmission of Trachipleistophora extenrec (Fungi: Microsporidia) between mammalian and insect hosts.
Parasitology Research. Roč. 108, č. 6 (2011), 1565-1573. ISSN 0932-0113. E-ISSN 1432-1955
R&D Projects: GA ČR GD524/03/H133; GA ČR GA524/07/1003
Institutional research plan: CEZ:AV0Z60220518
Keywords : NOSEMA-ALGERAE * BRACHIOLA-ALGERAE * AIDS PATIENT * HOMINIS * INFECTION * PATHOGEN * DIPTERA * ULTRASTRUCTURE * CULICIDAE * SEQUENCES
Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine
Impact factor: 2.149, year: 2011

Spores of Trachipleistophora extenrec, originally isolated from the muscles of the Madagascan insectivore Hemicentetes semispinosus and maintained by serial passage in SCID mice, were fed to larvae of the Egyptian cotton leafworm Spodoptera littoralis. Extensive infection of larval tissues ensued and caused larval and pupal mortality. The development of T. extenrec in the insect host, studied both by light and electron microscopy, followed generally the same life cycle as in the mammalian host. However, some differences in the fine structure of the parasite were found. Spores isolated from the insect host caused infection of SCID mice when injected intramuscularly. Our results suggest that T. extenrec may be originally an insect microsporidian. This is corroborated by its structural similarity and phylogenetic relationship to 2 other microsporidia having insects either as unique hosts (Vavraia culicis) or being able to infect both mammalian and insect host (Trachipleistophora hominis)
Permanent Link: http://hdl.handle.net/11104/0200181