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Facilitation of glutamate and GABA release by P2X receptor activation in supraoptic neurons from freshly isolated rat brain slices
- 1.0364772 - FGÚ 2012 RIV GB eng J - Journal Article
Vávra, Vojtěch - Bhattacharya, Anirban - Zemková, Hana
Facilitation of glutamate and GABA release by P2X receptor activation in supraoptic neurons from freshly isolated rat brain slices.
Neuroscience. Roč. 188, - (2011), s. 1-12. ISSN 0306-4522. E-ISSN 1873-7544
R&D Projects: GA AV ČR(CZ) IAA500110910; GA ČR(CZ) GA305/07/0681; GA ČR(CZ) GD305/08/H037; GA MŠMT(CZ) LC554
Institutional research plan: CEZ:AV0Z50110509
Keywords : ATP * purinergic P2X receptors * GABA * glutamate * supraoptic nucleus * patch clamp
Subject RIV: ED - Physiology
Impact factor: 3.380, year: 2011
The supraoptic nuclei (SON) of the hypothalamus receive an excitatory input that uses ATP as neurotransmitter. Voltage clamp recordings from neurons in rat hypothalamic slices showed that presynaptic ATP-stimulated P2X2 and P2X4 receptors modulate glutamate and GABA release and control the electrical excitability of SON neurons
Permanent Link: http://hdl.handle.net/11104/0200161
Number of the records: 1