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A periadventitial sirolimus-releasing mesh decreased intimal hyperplasia in a rabbit model

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    0364508 - FGÚ 2012 RIV CZ eng J - Journal Article
    Skalský, I. - Filová, Elena - Szárszoi, O. - Pařízek, Martin - Lytvynets, Andrej - Malušková, J. - Lodererová, A. - Brynda, Eduard - Lisá, Věra - Burdíková, Zuzana - Čapek, Martin - Pirk, J. - Bačáková, Lucie
    A periadventitial sirolimus-releasing mesh decreased intimal hyperplasia in a rabbit model.
    Physiological Research. Roč. 60, č. 3 (2011), s. 585-588. ISSN 0862-8408. E-ISSN 1802-9973
    R&D Projects: GA MZd(CZ) NR9358; GA ČR(CZ) GA102/08/0691; GA ČR(CZ) GAP108/11/0794; GA MŠMT(CZ) 1M0510
    Institutional research plan: CEZ:AV0Z50110509; CEZ:AV0Z40500505
    Keywords : intimal hyperplasia * controlled release * sirolimus * perivascular drug delivery system
    Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
    Impact factor: 1.555, year: 2011

    In the study, the effect of sirolimus-releasing mesh on development of intimal hyperplasia in rats was evaluated. Sirolimus released from the mesh caused significant reduction of intima thickness of autologous vein graft interposed into the arterial bed in rabbits after 3 weeks
    Permanent Link: http://hdl.handle.net/11104/0199977

     
     
Number of the records: 1  

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