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Model of fasciculation and sorting in mixed populations of axons
- 1.0364482 - FGÚ 2012 RIV US eng J - Journal Article
Chaudhuri, D. - Borowski, P. - Zápotocký, Martin
Model of fasciculation and sorting in mixed populations of axons.
Physical Review E. Roč. 84, č. 2 (2011), e021908. ISSN 1539-3755
R&D Projects: GA MŠMT(CZ) LC554
Institutional research plan: CEZ:AV0Z50110509
Keywords : axon guidance * neurogenesis * mathematical model
Subject RIV: FH - Neurology
Impact factor: 2.255, year: 2011
We extend a recently proposed mathematical model aiming to describe the formation of fascicles of axons during neural development. We generalize the model to adhesive interactions of finite strengths and to multiple types of axons with type-specific interactions. With distance in the direction of axon growth, the mean fascicle size and emergent time scales grow monotonically, while the degree of sorting of fascicles by axon type has a maximum at a finite distance.To understand the emergence of slow time scales, we develop an analytical framework to analyze the interaction between neighboring fascicles
Permanent Link: http://hdl.handle.net/11104/0199959
Number of the records: 1