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Vasodilator efficiency of endogenous prostanoids, Ca2+-activated K+ channels and nitric oxide in rats with spontaneous, salt-dependent or NO-deficient hypertension
- 1.0364293 - FGÚ 2012 RIV JP eng J - Journal Article
Behuliak, Michal - Pintérová, Mária - Kuneš, Jaroslav - Zicha, Josef
Vasodilator efficiency of endogenous prostanoids, Ca2+-activated K+ channels and nitric oxide in rats with spontaneous, salt-dependent or NO-deficient hypertension.
Hypertension Research. Roč. 34, č. 8 (2011), s. 968-975. ISSN 0916-9636. E-ISSN 1348-4214
R&D Projects: GA ČR(CZ) GA305/09/0336; GA AV ČR(CZ) IAA500110902; GA MŠMT(CZ) 1M0510
Institutional research plan: CEZ:AV0Z50110509
Keywords : Ca2+-activated K+ channels * nitric oxide-dependent vasodilatation * prostacyclin
Subject RIV: ED - Physiology
Impact factor: 2.576, year: 2011
Our data suggested that there is a compensatory activation of vasodilator prostanoids and Ca(2+)-activated K(+) channels in rats with experimental hypertension, whereas NO-dependent vasodilatation is not augmented. Thus, the overall activity of vasodilator systems failed to compensate for augmented sympathetic vasoconstriction in hypertensive animals
Permanent Link: http://hdl.handle.net/11104/0199814
Number of the records: 1