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Noise exposure during early development influences the acoustic startle reflex in adult rats
- 1.0363983 - ÚEM 2012 RIV US eng J - Journal Article
Rybalko, Natalia - Bureš, Zbyněk - Burianová, Jana - Popelář, Jiří - Grécová, Jolana - Syka, Josef
Noise exposure during early development influences the acoustic startle reflex in adult rats.
Physiology and Behavior. Roč. 102, č. 5 (2011), s. 453-458. ISSN 0031-9384. E-ISSN 1873-507X
R&D Projects: GA ČR GA309/07/1336
Grant - others:GA ČR(CZ) GD309/08/H079
Institutional research plan: CEZ:AV0Z50390512
Keywords : noise exposure * startle reflex
Subject RIV: FH - Neurology
Impact factor: 2.869, year: 2011
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0363983_01.pdf
In the present study, the behavioral consequences of brief noise exposure during the critical period in rats were assessed in adult rats using the acoustic startle reflex and prepulse inhibition of the acoustic startle reflex. The results showed that although the hearing hresholds in exposed and control animals were not different, a reduced strength of the startle reflex and markedly different efficacy of prepulse inhibition were observed between both groups of animals. Our findings demonstrate that brief noise exposure in rat pups results in altered behavioral responses to sounds in adulthood, indicating, accompanied by anomalies in intensity coding and loudness perception.
Permanent Link: http://hdl.handle.net/11104/0199588
Number of the records: 1