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Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-l-yl)methyl]uracils through the "click" protocol

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    0363593 - ÚOCHB 2012 RIV CZ eng J - Journal Article
    Jansa, Petr - Špaček, Petr - Votruba, Ivan - Břehová, Petra - Dračínský, Martin - Klepetářová, Blanka - Janeba, Zlatko
    Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-l-yl)methyl]uracils through the "click" protocol.
    Collection of Czechoslovak Chemical Communications. Roč. 76, č. 9 (2011), s. 1121-1131. ISSN 0010-0765
    R&D Projects: GA MŠMT 1M0508; GA AV ČR KJB400550903
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : nucleosides * nucleotides * heterocycles * biological activity * phosphorus
    Subject RIV: CC - Organic Chemistry
    Impact factor: 1.283, year: 2011

    The preparation of several triazolo acyclic nucleosides and triazolo acyclic nucleoside phosphonates is described using an efficient one-pot Cu(I)-catalyzed azide alkyne Huisgen "click" cycloaddition.
    Permanent Link: http://hdl.handle.net/11104/0199352

     
     
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