On-line, real time monitoring of exhaled trace gases by SIFT-MS in the perioperative setting: a feasibility study

0363284 - ÚFCH JH 2012 RIV GB eng J - Journal Article
Boshier, P. R. - Cushnir, J. R. - Mistry, V. - Knaggs, A. - Španěl, Patrik - Smith, D. - Hanna, G. B.
On-line, real time monitoring of exhaled trace gases by SIFT-MS in the perioperative setting: a feasibility study.
Analyst. Roč. 136, č. 16 (2011), s. 3233-3237. ISSN 0003-2654. E-ISSN 1364-5528
Institutional research plan: CEZ:AV0Z40400503
Keywords : SIFT-MS * breath analysis
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 4.230, year: 2011

A study is described of the first on line, real time analyses of the exhaled breath of five anaesthetized patients during the complete perioperative periods of laparoscopic surgery. These breath analyses were achieved using a selected ion flow tube, SIFT-MS, instrument, located in the operating theatre at an acceptable distance from the operating table, and coupled to the endotracheal tube in the ventilation circuit via a 5 metre long capillary tube. Thus, inhalation/exhalation breathing cycles, set to be at a frequency of 10 per minute, were sampled continuously for water vapour, the metabolites acetone and isoprene and the propofol used to induce anaesthesia for each operating period that ranged from 20 min (shortest) to 80 min (longest). Whilst there was some loss of water vapour along the long sampling line, the concentrations of the other trace compounds were not diminished.
Permanent Link: http://hdl.handle.net/11104/0199269