Breath acetone concentration; biological variability and the influence of diet

0363280 - ÚFCH JH 2012 RIV GB eng J - Journal Article
Španěl, Patrik - Dryahina, Kseniya - Rejšková, A. - Chippendale, T. W. E. - Smith, D.
Breath acetone concentration; biological variability and the influence of diet.
Physiological Measurement. Roč. 32, č. 8 (2011), N23-N31. ISSN 0967-3334. E-ISSN 1361-6579
R&D Projects: GA ČR GP203/09/P172
Institutional research plan: CEZ:AV0Z40400503
Keywords : acetone * breath * ketogenic diet
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 1.677, year: 2011

Previous measurements of acetone concentrations in the exhaled breath of healthy individuals and the small amount of comparable data for individuals suffering from diabetes are briefly reviewed as a prelude to the presentation of new data on the sporadic and wide variations of breath acetone that occur in ostensibly healthy individuals. Data are also presented which show that following a ketogenic diet taken by eight healthy individuals their breath acetone concentrations increased up to five times over the subsequent 6 h. Similarly, the breath acetone increased six and nine times when a low carbohydrate diet was taken by two volunteers and remained high for the several days for which the diet was continued. These new data, together with the previous data, clearly indicate that diet and natural intra-individual biological and diurnal variability result in wide variations in breath acetone concentration.
Permanent Link: http://hdl.handle.net/11104/0199267