Number of the records: 1
Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis
- 1.0361620 - MBÚ 2012 RIV GB eng J - Journal Article
Kverka, Miloslav - Rossmann, Pavel - Tlaskalová-Hogenová, Helena - Klimešová, Klára - Jharap, B. - de Boer, N. - Vos, R. M. - van Bodegraven, A.A. - Lukáš, M. - Mulder, Ch.J.
Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis.
BMC Gastroenterology. Roč. 11, č. 1 (2011), s. 1-9. E-ISSN 1471-230X
R&D Projects: GA AV ČR KJB500200904; GA ČR GD310/08/H077; GA MŠMT 2B06155
Institutional research plan: CEZ:AV0Z50200510
Keywords : INFLAMMATORY-BOWEL-DISEASE * NODULAR REGENERATIVE HYPERPLASIA * LOW-DOSE 6-THIOGUANINE
Subject RIV: EC - Immunology
Impact factor: 2.422, year: 2011
Background: Oral thiopurines are effective and widely used in treatment of inflammatory bowel disease (IBD) in humans, although their use is limited due the development of adverse events. Here, we examine the efficacy and toxicity of oral treatment with 6-tioguanine (6-TG) and azathioprine (AZA) in a murine model of IBD
Permanent Link: http://hdl.handle.net/11104/0006519
Number of the records: 1