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Neonatal colonization of mice with Lactobacillus plantarum producing the aeroallergen Bet v 1 biases towards Th1 and T-regulatory responses upon systemic sensitization
- 1.0361615 - MBÚ 2012 RIV DK eng J - Journal Article
Schwarzer, Martin - Repa, A. - Daniel, C. - Schabussova, I. - Hrnčíř, Tomáš - Pot, B. - Štěpánková, Renata - Hudcovic, Tomáš - Pollak, A. - Tlaskalová, Helena - Wiedermann, U. - Kozáková, Hana
Neonatal colonization of mice with Lactobacillus plantarum producing the aeroallergen Bet v 1 biases towards Th1 and T-regulatory responses upon systemic sensitization.
Allergy. Roč. 66, č. 3 (2011), 368-375. ISSN 0105-4538. E-ISSN 1398-9995
R&D Projects: GA AV ČR IAA500200710; GA ČR GA303/09/0449; GA MŠMT 2B06155
Institutional research plan: CEZ:AV0Z50200510
Keywords : germ-free mice * allergy * mucosal immunity
Subject RIV: EC - Immunology
Impact factor: 6.271, year: 2011
The use of recombinant lactic acid bacteria (LAB) as vehicles for mucosal delivery of recombinant allergens is an attractive concept for antigen-defined allergy prevention/treatment. Interventions with LAB are of increasing interest early in life when immune programming is initiated. Here, we investigated the effect of neonatal colonization with a recombinant LAB producing the major birch pollen allergen Bet v 1 in a murine model of type I allergy
Permanent Link: http://hdl.handle.net/11104/0198892
Number of the records: 1