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The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination reactions of purines
- 1.0360741 - ÚOCHB 2012 RIV GB eng J - Journal Article
Čechová, Lucie - Jansa, Petr - Šála, Michal - Dračínský, Martin - Holý, Antonín - Janeba, Zlatko
The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination reactions of purines.
Tetrahedron. Roč. 67, č. 5 (2011), s. 866-871. ISSN 0040-4020. E-ISSN 1464-5416
R&D Projects: GA MŠMT 1M0508; GA AV ČR KJB400550903
Institutional research plan: CEZ:AV0Z40550506
Keywords : microwave-assisted synthesis * DMF * formamides * dehalogenative amination * purines
Subject RIV: CC - Organic Chemistry
Impact factor: 3.025, year: 2011
The microwave-assisted decomposition of DMF was thoroughly studied and the reaction conditions (temperature, solvent effect, and effect of additives such as acids, bases, and salts) were optimized for its use in amination reactions. The applicability of this expedient methodology in purine chemistry and with various formamides is demonstrated.
Permanent Link: http://hdl.handle.net/11104/0198223
Number of the records: 1