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Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters

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    0360704 - MBÚ 2012 RIV GB eng J - Journal Article
    Bossu, I. - Šulc, Miroslav - Křenek, Karel - Dufour, E. - Garcia, J. - Berthet, N. - Dumy, P. - Křen, Vladimír - Renaudet, O.
    Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters.
    Organic & Biomolecular Chemistry. Roč. 9, č. 6 (2011), 1948-1959. ISSN 1477-0520. E-ISSN 1477-0539
    R&D Projects: GA MŠMT(CZ) LC06010; GA ČR GD305/09/H008
    Institutional research plan: CEZ:AV0Z50200510
    Keywords : T-CELL EPITOPE * CHEMOSELECTIVE LIGATION * B-CELL
    Subject RIV: CC - Organic Chemistry
    Impact factor: 3.696, year: 2011

    Synthetic glycoclusters and their related biological applications have stimulated increasing interest over the last decade. As a prerequisite to discovering active and selective therapeuticals, the development of multivalent glycoconjugates with diverse topologies is faced with inherent synthetic and structural characterisation difficulties. Here we describe a new series of molecularly-defined glycoclusters that were synthesized in a controlled manner using a robust and versatile divergent protocol
    Permanent Link: http://hdl.handle.net/11104/0198192

     
     
Number of the records: 1  

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