Selected ion flow tube, SIFT, studies of the reactions of H3O+, NO+ and O2 + with some biologically active isobaric compounds in preparation for SIFT-MS analyses

0359553 - ÚFCH JH 2015 RIV NL eng J - Journal Article
Smith, D. - Chippendale, T. W. E. - Španěl, Patrik
Selected ion flow tube, SIFT, studies of the reactions of H3O+, NO+ and O2 + with some biologically active isobaric compounds in preparation for SIFT-MS analyses.
International Journal of Mass Spectrometry. Roč. 303, 2-3 (2011), s. 81-89. ISSN 1387-3806. E-ISSN 1873-2798
R&D Projects: GA ČR GA202/09/0800; GA ČR GA203/09/0256
Institutional research plan: CEZ:AV0Z40400503
Keywords : SIFT-MS * ion-molecule reactions * proton transfers
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 2.549, year: 2011

A study of the reactions of H3O+, NO+ and O2+ ions with two groups of four isobaric, biologically active compounds with molecular weights, MW, of 86u and 88u has been carried out using the selected ion flow tube, SIFT, technique in preparation for the analyses of these compounds in the headspace of bacterial and cell cultures using SIFT-MS. These compounds are: MW 86u: 2,3 butanedione (diacetyl), C4H6O2; allyl ethyl ether, C5H10O, cyclopropane carboxylic acid, C4H6O2: γ-butyrolactone, C4H6O2. MW 88u: 3-hydroxybutanone (acetoin), C4H8O2; n-butyric acid, C4H8O2; ethyl acetate, C4H8O2; pyruvic acid, C3H4O3. All 24 reactions proceed at the gas kinetic rate, the dominant primary product ions of the H3O+ reactions being the protonated reactant molecules, MH+ with a common mass-to-charge ratio, m/z, in each group of isobaric compounds;...
Permanent Link: http://hdl.handle.net/11104/0197324