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Preventive dietary potassium supplementation in young salt-sensitive Dahl rats attenuates development of salt hypertension by decreasing sympathetic vasoconstriction

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    0359269 - FGÚ 2012 RIV US eng J - Journal Article
    Zicha, Josef - Dobešová, Zdenka - Behuliak, Michal - Kuneš, Jaroslav - Vaněčková, Ivana
    Preventive dietary potassium supplementation in young salt-sensitive Dahl rats attenuates development of salt hypertension by decreasing sympathetic vasoconstriction.
    Acta Physiologica. Roč. 202, č. 1 (2011), s. 29-38. ISSN 1748-1708. E-ISSN 1748-1716
    R&D Projects: GA ČR(CZ) GA305/08/0139; GA ČR(CZ) GA305/09/0336; GA AV ČR(CZ) IAA500110902; GA MŠMT(CZ) 1M0510
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : dietary potassium * nitric oxide * prostacyclin * calcium-activated potassium channels
    Subject RIV: ED - Physiology
    Impact factor: 3.090, year: 2011

    The attenuation of enhanced sympathetic vasoconstriction is the principal mechanism of antihypertensive action exerted by preventive potassium supplementation in immature Dahl rats. Dietary potassium supplementation has no preventive effects on BP in adult salt-loaded animals or no therapeutic effects on established salt hypertension in young rats
    Permanent Link: http://hdl.handle.net/11104/0197082

     
     
Number of the records: 1  

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