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8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase

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    0359018 - ÚOCHB 2012 RIV GB eng J - Journal Article
    Mařák, David - Otmar, Miroslav - Votruba, Ivan - Dračínský, Martin - Krečmerová, Marcela
    8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase.
    Bioorganic and Medicinal Chemistry Letters. Roč. 21, č. 2 (2011), s. 652-654. ISSN 0960-894X. E-ISSN 1464-3405
    R&D Projects: GA MŠMT 1M0508
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : 8-aza-7,9-dideazaxanthine * pyrrolo[3,4-d]pyrimidine * nucleotide analog
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.554, year: 2011

    3- and 8-(8-phosphonooctyl)-8-aza-7,9-dideazaxanthine, and 1,8-bis(8-aza-7,9-dideazaxanthin-8-yl)octane were prepared and found to inhibit bacterial and human thymidine phosphorylase.
    Permanent Link: http://hdl.handle.net/11104/0196896

     
     
Number of the records: 1  

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