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Rebound increase in seizure susceptibility but not isolation-induced calls after single administration of clonazepam and Ro 19-8022 in infant rats

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    0358971 - FGÚ 2012 RIV US eng J - Journal Article
    Mikulecká, Anna - Mareš, Pavel - Kubová, Hana
    Rebound increase in seizure susceptibility but not isolation-induced calls after single administration of clonazepam and Ro 19-8022 in infant rats.
    Epilepsy and Behavior. Roč. 20, č. 1 (2011), s. 12-19. ISSN 1525-5050. E-ISSN 1525-5069
    R&D Projects: GA ČR(CZ) GA305/09/0846
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : Pentylenetetrazole-induced seizure * ultrasonic vocalization * motor performance * Clonazepam * Ro 19-8022 * immature rats
    Subject RIV: FH - Neurology
    Impact factor: 2.335, year: 2011

    Clonazepam and Ro 19-8022 administration led to rebound phenomena in immature 12-day-old rats. Ultrasonic vocalizations were suppressed after both drugs. Dissociation between rebound proconvulsant and anxiolytic-like effects was found
    Permanent Link: http://hdl.handle.net/11104/0196861

     
     
Number of the records: 1  

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