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Perivascular sirolimus-delivery system

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    0358898 - FGÚ 2012 RIV GB eng J - Journal Article
    Filová, Elena - Pařízek, Martin - Olšovská, Jana - Kameník, Zdeněk - Brynda, Eduard - Riedel, Tomáš - Vandrovcová, Marta - Lisá, Věra - Machová, Luďka - Skalský, I. - Szárszoi, O. - Suchý, Tomáš - Bačáková, Lucie
    Perivascular sirolimus-delivery system.
    International Journal of Pharmaceutics. Roč. 404, 1-2 (2011), s. 94-101. ISSN 0378-5173. E-ISSN 1873-3476
    R&D Projects: GA MŠMT(CZ) 1M0510; GA MZd(CZ) NR9358
    Institutional research plan: CEZ:AV0Z50110509; CEZ:AV0Z50200510; CEZ:AV0Z30460519; CEZ:AV0Z40500505
    Keywords : vascular smooth muscle cells * drug delivery * rapamycin
    Subject RIV: EI - Biotechnology ; Bionics
    Impact factor: 3.350, year: 2011

    Polyester Mesh I was coated with purasorb. Mesh II was coated with two copolymer layers. Both meshes inhibited proliferation of rat vascular smooth muscle cells during 14-day culture in vitro and preserved excellent cell viability. Newly developed sirolimus-releasing perivascular meshes are promising devices for preventing autologous graft restenosis
    Permanent Link: http://hdl.handle.net/11104/0196810

     
     
Number of the records: 1  

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