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Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA
- 1.0358135 - BFÚ 2011 RIV GB eng J - Journal Article
Malina, Jaroslav - Kašpárková, J. - Farrell, N.P. - Brabec, Viktor
Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.
Nucleic Acids Research. Roč. 39, č. 2 (2011), s. 720-728. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA MŠMT(CZ) ME10066
Grant - others:GA MŠk(CZ) LC06030; GA MŠk(CZ) OC09018; GA AV ČR(CZ) KAN200200651
Program: LC; KA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : BBR3464 * DNA * cross-link
Subject RIV: BO - Biophysics
Impact factor: 8.026, year: 2011
The results show that cross-links originally formed by BBR3464 in one strand of DNA can spontaneously translocate from one DNA strand to its complementary counterpart, which may evoke walking of the platinum complex on DNA molecule.
Permanent Link: http://hdl.handle.net/11104/0196242
Number of the records: 1