Assessing multilocus introgression patterns: a case study on the mouse X chromosome in Central Europe

0355994 - ÚBO 2012 RIV US eng J - Journal Article
Macholán, Miloš - Baird, S. J. E. - Dufková, Petra - Munclinger, P. - Vošlajerová Bímová, Barbora - Piálek, Jaroslav
Assessing multilocus introgression patterns: a case study on the mouse X chromosome in Central Europe.
Evolution. Roč. 65, č. 5 (2011), s. 1428-1446. ISSN 0014-3820. E-ISSN 1558-5646
R&D Projects: GA ČR GA206/08/0640
Institutional research plan: CEZ:AV0Z50450515; CEZ:AV0Z60930519
Keywords : genetic conflict * hybrid zone movement * sex biased introgression * mice * X chromosome
Subject RIV: EG - Zoology
Impact factor: 5.146, year: 2011

Relating introgression along a chromosome to evolutionary process is challenging: while reduced introgression regions may indicate speciation genes, this pattern may be obscured by asymmetric introgression of linked invasive genes. We compare Barton’s concordance fitting model and two-dimensional (2D) geographic analyses, for 24 X chromosome loci of 2873 mice from the central-European house mouse hybrid zone. In 2D, 14 loci show linear contact, seven precisely matching previous studies. Four show introgression islands to the east of the zone, suggesting past westward zone movement, two show westward salients. Barton’s concordance both recovers and refines this information. A region of reduced introgression on the central X is supported, despite X centromere-proximal male-biased westward introgression matching a westward 2D geographic salient. Genomic clines results are consistent regarding introgression asymmetries, but otherwise more difficult to interpret.
Permanent Link: http://hdl.handle.net/11104/0194631