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Structural Insights into the Function of P2X4: An ATP-Gated Cation Channel of Neuroendocrine Cells
- 1.0355649 - FGÚ 2011 RIV US eng J - Journal Article
Stojilkovic, S. S. - Yan, Z. - Obšil, T. - Zemková, Hana
Structural Insights into the Function of P2X4: An ATP-Gated Cation Channel of Neuroendocrine Cells.
Cellular and Molecular Neurobiology. Roč. 30, č. 8 (2010), s. 1251-1258. ISSN 0272-4340. E-ISSN 1573-6830
R&D Projects: GA AV ČR(CZ) IAA500110910; GA AV ČR(CZ) IAA501110801
Institutional research plan: CEZ:AV0Z50110509
Keywords : ATP-gated receptor channels * gating * ivermectin
Subject RIV: ED - Physiology
Impact factor: 2.423, year: 2010
The P2X4 receptor is a member of a family of ATP-gated cation channels, which are composed of three subunits, each having two transmembrane domains linked by a large extracellular loop and intracellularly located N- and C-termini. Recent crystallization of zebrafish P2X4 not only provided the possibility for re-interpretation of data generated by site-directed mutagenesis but also to progress in further work on structural-functional characterization
Permanent Link: http://hdl.handle.net/11104/0194368
Number of the records: 1