Enhancement of Thymoquinone Concentration in Black Cumin Extract Using Supercritical Fluid Fractionation

0355265 - ÚCHP 2011 RIV IT eng C - Conference Paper (international conference)
Sajfrtová, Marie - Topiař, Martin - Karban, Jindřich - Sovová, Helena
Enhancement of Thymoquinone Concentration in Black Cumin Extract Using Supercritical Fluid Fractionation.
Proceedings. Salerno: Centro Stampa di Ateneo, 2010 - (Reverchon, E.), s. 127-132. ISBN 88-7897-040-9.
[Conference on Supercritical Fluids and Their Applications /9./. Sorrento (IT), 05.09.2010-08.09.2010]
R&D Projects: GA ČR GA525/08/1179
Institutional research plan: CEZ:AV0Z40720504
Keywords : supercritical fluid extraction * thymoquinone * carbon dioxide
Subject RIV: CI - Industrial Chemistry, Chemical Engineering

Supercritical fluid extraction (SFE) using carbon dioxide has been studied as a modern, environmentally friendly method to separate high-added value compounds from plants that allows dissolving preferably the required compounds by changing extraction conditions. SFE helps to obtain extracts with both TQ concentration and biological activity significantly higher than those isolated by conventional separation methods. This work is focused on TQ from black cumin seeds. To obtain higher concentration of the desired compound, SFE was applied with consequent fractionation of the extract in two separators maintained at different pressure and temperature. The efficiency of SFE in terms of TQ concentration in extract and yield was compared with the products of hydrodistillation and Soxhlet extraction.
Permanent Link: http://hdl.handle.net/11104/0194077