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Antitumor activity of N-acetyl-D-glucosamine-substituted glycoconjugates and combined therapy with keyhole limpet hemocyanin in B16F10 mouse melanoma model

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    0354141 - MBÚ 2011 RIV CZ eng J - Journal Article
    Huliková, Katarína - Grobárová, Valeria - Křivohlavá, Romana - Fišerová, Anna
    Antitumor activity of N-acetyl-D-glucosamine-substituted glycoconjugates and combined therapy with keyhole limpet hemocyanin in B16F10 mouse melanoma model.
    Folia Microbiologica. Roč. 55, č. 5 (2010), s. 528-532. ISSN 0015-5632. E-ISSN 1874-9356
    R&D Projects: GA AV ČR IAA500200620; GA AV ČR IAA601680801; GA ČR GD310/08/H077
    Institutional research plan: CEZ:AV0Z50200510
    Keywords : IN-VIVO * CYTOTOXICITY * LIGANDS
    Subject RIV: EC - Immunology
    Impact factor: 0.977, year: 2010

    N-acetyl-D-glucosamine-substituted calix[4]arene (GN4C), ligand for NKR-P1 receptor of NK cells, significantly reduced the tumor growth and prolonged survival of experimental animals in mouse B16F10 melanoma model. The treatment with non-specific immunostimulator keyhole limpet hemocyanin did not potentiate GN4C effects
    Permanent Link: http://hdl.handle.net/11104/0193207

     
     
Number of the records: 1  

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