Handbook of Nutritional Biochemistry. Genomics, Metabolimics and Food Supply

0353920 - ÚFCH JH 2011 RIV US eng M - Monography Chapter
Navrátil, Tomáš - Kohlíková, E. - Petr, M. - Přistoupilová, K.
Effect of creatine applied as food supplement on human metabolism.
Handbook of Nutritional Biochemistry. Genomics, Metabolimics and Food Supply. New York: Nova Sicence Publ., Inc, 2010 - (Haugen, S.; Meijer, S.), s. 317-338. Nutritrition and Diet Research Progress Series. ISBN 978-1-60741-916-7
R&D Projects: GA ČR GA203/07/1195; GA AV ČR IAA400400806
Institutional research plan: CEZ:AV0Z40400503
Keywords : creatine * creatinine * folates
Subject RIV: CF - Physical ; Theoretical Chemistry

In our short-term study we have observed changes in the metabolism of two-carbon (2C) units and of thiolic substances 4 to 6 hours after CR supplementation. The level of thiodiglycolic acid (TDGA) in urine increased rapidly and then decreased again to the original level. At the same time the pH values of urine increased by 1.5 units. The level of TDGA in urine is a marker of disturbance in metabolic pathways of 2C units and of thiolic compounds.
Permanent Link: http://hdl.handle.net/11104/0193031