Quantum chemical studies of nucleic acids: Can we construct a bridge to the RNA structural biology and bioinformatics communities?

0353812 - BFÚ 2011 RIV US eng J - Journal Article
Šponer, Jiří - Šponer, Judit E. - Petrov, A.I. - Leontis, N.B.
Quantum chemical studies of nucleic acids: Can we construct a bridge to the RNA structural biology and bioinformatics communities?
Journal of Physical Chemistry B. Roč. 114, č. 48 (2010), s. 15723-15741. ISSN 1520-6106. E-ISSN 1520-5207
R&D Projects: GA AV ČR(CZ) IAA400040802; GA ČR(CZ) GA203/09/1476; GA ČR(CZ) GAP208/10/2302; GA MŠMT(CZ) LC06030
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : quantum chemistry * RNA bioinformatics * nucleic acids
Subject RIV: BO - Biophysics
Impact factor: 3.603, year: 2010

This invited feature article provides a side-by-side introduction for two research fields: quantum chemical calculations of molecular interactions in nucleic acids and RNA structural bioinformatics. Our main aim is to demonstrate that these research areas, while largely separated in contemporary literature, have substantial potential to complement each other that could significantly contribute to our understanding of the exciting world of nucleic acids.
Permanent Link: http://hdl.handle.net/11104/0006243