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Biology of Rhodococcus

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    0352774 - MBÚ 2011 RIV DE eng M - Monography Chapter
    Martínková, Ludmila - Pátek, Miroslav - Veselá, Alicja Barbara - Kaplan, Ondřej - Uhnáková, Bronislava - Nešvera, Jan
    Catabolism of Nitriles in Rhodococcus.
    Biology of Rhodococcus. Berlín: Springer Verlag, 2010 - (Alvarez, H.; Steinbuchel, A.), s. 172-206. ISBN 978-3-642-12936-0
    R&D Projects: GA MPO FT-TA5/043; GA MŠMT(CZ) LC06010; GA MŠMT OC09046
    Institutional research plan: CEZ:AV0Z50200510
    Keywords : nitrile hydratase * nitrilase * rhodococcus
    Subject RIV: EE - Microbiology, Virology

    The enzymes of nitrile catabolism in Rhodococcus include nitrilases and nitrile hydratases/amidase systems. According to their cofactor, nitrile hydratases are classified into Fe-type and Co-type subfamilies, which are typically produced by Rhodococcus erythropolis and Rhodococcus rhodochrous, respectively. The latter species is also the typical source of nitrilases, most of which strongly prefer aromatic substrates. The organization of the nitrilase, nitrile hydratase, amidase and relevant regulatory genes, and mechanisms of their expression control are shown. The unique structural and physico-chemical properties of these enzymes (subunit aggregation, Fe-type nitrile hydratase photoreactivity) are described. The overview of nitrile-converting enzyme applications emphasizes their use in the biodegradation of aliphatic nitriles and benzonitrile herbicides
    Permanent Link: http://hdl.handle.net/11104/0192202

     
     
Number of the records: 1  

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