0351849 - FGÚ 2011 RIV NL eng J - Journal Article
Huang, X. - Morse, L. R. - Xu, C. - Zahrádka, Jaromír - Sychrová, Hana - Stashenko, P. - Fan, F. - Battaglino, R. A.
Mutational analysis of NHAoc/NHA2 in Saccharomyces cerevisiae.
Biochimica et Biophysica Acta-General Subjects. Roč. 1800, č. 12 (2010), s. 1241-1247. ISSN 0304-4165. E-ISSN 1872-8006
R&D Projects: GA AV ČR(CZ) IAA500110801; GA MŠMT(CZ) OC10012
Institutional research plan: CEZ:AV0Z50110509
Keywords : heterologous expression * trast * human NHA2
Subject RIV: CE - Biochemistry
Impact factor: 4.663, year: 2010

The activity of human NHAoc protein and its mutated forms has been characterized upon heterologous expression in a Saccharomyces cerevisiaae mutant strain lacking its own sodium and potassium exporters. This approach identified amino-acid residues crucial for the activity of the studied protein and contributed to the eleucidation of the NHAoc protein structure
Permanent Link: http://hdl.handle.net/11104/0191505