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Surface modification of polyimide sheets for regenerative medicine applications
- 1.0351527 - MBÚ 2011 RIV US eng J - Journal Article
van Vlierberghe, S. - Šírová, Milada - Rossmann, Pavel - Thielecke, H. - Boterberg, V. - Říhová, Blanka - Schacht, E. - Dubruel, P.
Surface modification of polyimide sheets for regenerative medicine applications.
Biomacromolecules. Roč. 11, č. 10 (2010), s. 2731-2739. ISSN 1525-7797. E-ISSN 1526-4602
Institutional research plan: CEZ:AV0Z50200510
Keywords : NEURAL IMPLANT * POLYMER-FILMS * BIOCOMPATIBILITY
Subject RIV: CE - Biochemistry
Impact factor: 5.327, year: 2010
The in vivo biocompatibility of the modified PI implants was demonstrated using a subcutaneous murine model. As a proof of concept, we studies the immobolization of methacrylamide modified gelatin on the PI.The subcutaneous implantation in mice indicated that both modification strategies resulted in biocompatible materials, inducing only limited cellular infiltration to the surrounding tissue
Permanent Link: http://hdl.handle.net/11104/0006167
Number of the records: 1