Antibacterial properties of Ag-doped hydroxyapatite layersprepared by PLD method

0351504 - FZÚ 2011 RIV DE eng J - Journal Article
Jelínek, Miroslav - Kocourek, Tomáš - Jurek, Karel - Remsa, Jan - Mikšovský, Jan - Weiserová, Marie - Strnad, J. - Luxbacher, T.
Antibacterial properties of Ag-doped hydroxyapatite layersprepared by PLD method.
Applied Physics A - Materials Science & Processing. Roč. 101, č. 4 (2010), s. 615-620. ISSN 0947-8396. E-ISSN 1432-0630
Institutional research plan: CEZ:AV0Z10100522; CEZ:AV0Z50200510
Keywords : antibacterial properties, * PLD * layers * silver-doped
Subject RIV: BM - Solid Matter Physics ; Magnetism
Impact factor: 1.765, year: 2010

Thin hydroxyapatite (HA), silver-doped HA and silver layers were prepared using a pulsed laser deposition method. Doped layers were ablated from silver/HA targets. Amorphous and crystalline films of silver concentrations of 0.06 at.%, 1.2 at.%, 4.4 at.%, 8.3 at.% and 13.7 at.% were synthesized. Topology was studied using scanning electron microscopy and atomic force microscopy. Contact angle and zeta potential measurements were conducted to determine the wettability, surface free energy and electric surface properties. In vivo measurement (using Escherichia coli cells) of antibacterial properties of the HA, silver-doped HA and silver layers was carried out. The best antibacterial results were achieved for silver-doped HA layers of silver concentration higher than 1.2 at.%.
Permanent Link: http://hdl.handle.net/11104/0006166