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Interictal high-frequency oscillations indicate seizure onset zone in patients with focal cortical dysplasia

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    0351423 - ÚPT 2011 RIV NL eng J - Journal Article
    Brázdil, M. - Halámek, Josef - Jurák, Pavel - Daniel, P. - Kuba, R. - Chrastina, J. - Novák, Z. - Rektor, I.
    Interictal high-frequency oscillations indicate seizure onset zone in patients with focal cortical dysplasia.
    Epilepsy Research. Roč. 90, 1-2 (2010), s. 28-32. ISSN 0920-1211. E-ISSN 1872-6844
    R&D Projects: GA MŠMT ED0017/01/01
    Institutional research plan: CEZ:AV0Z20650511
    Keywords : epilepsy * hgh-frequency oscillations * intracerebral EEG
    Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
    Impact factor: 2.302, year: 2010

    Interictal high-frequency oscillations (HFO) were recently identified in recordings from depth macroelectrodes in epileptic patients. StereoEEG (SEEG) recordings were analyzed in four patients with medically intractable partial seizures due to focal cortical dysplasia type IIA. Characteristics of HFO within seizure onset zone (SOZ), irritative zone, and remote brain areas were investigated. Whilst the rate of occurrence for ripples (80-200 Hz) was significantly higher in recordings from within than outside the SOZ, the rate of fast ripples (200-450 Hz) was less reliable index of SOZ. Interestingly, the mean powers across subjects were significantly higher within than outside the SOZ in both ripple and fast ripple frequency ranges. Our study demonstrates a capacity of interictal HFO to detect the SOZ in focal cortical dysplasias. (C) 2010 Elsevier B.V. All rights reserved.
    Permanent Link: http://hdl.handle.net/11104/0191180

     
     
Number of the records: 1  

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