A label-free and portable multichannel surface plasmon resonance immunosensor for on site analysis of antibiotics in milk samples

0350666 - ÚFE 2011 RIV GB eng J - Journal Article
Fernández, F. - Hegnerová, Kateřina - Piliarik, Marek - Sanchez-Baeza, F. - Homola, Jiří - Marko, M.P.
A label-free and portable multichannel surface plasmon resonance immunosensor for on site analysis of antibiotics in milk samples.
Biosensors and Bioelectronics. Roč. 26, č. 4 (2010), s. 1231-1238. ISSN 0956-5663. E-ISSN 1873-4235
R&D Projects: GA AV ČR KAN200670701
Institutional research plan: CEZ:AV0Z20670512
Keywords : surface plasmon resonance * antibiotics * milk
Subject RIV: JB - Sensors, Measurment, Regulation
Impact factor: 5.361, year: 2010

This paper describes the development of a novel 6-channel SPR biosensor based on the plasmon of gold diffraction grating surface for multianalyte antibiotic detection in milk. Representative congeners from three antibiotic families (FQs: fluoroquinolones, SAs: sulfonamides and CAP: phenicols) were chosen for this study. The detection limits were in buffer: enrofloxacin 0.30µg/L; sulfapyridine 0.29µg/L; chloramphenicol 0.26µg/L. Milk samples can be analyzed directly by diluting the sample five times with water.
Permanent Link: http://hdl.handle.net/11104/0190606