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Synergistic action of doxorubicin bound to the polymeric carrier based on N-(2-hydroxypropyl)methacrylamide copolymers through and amide or hydrazone bond

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    0350325 - MBÚ 2011 RIV US eng J - Journal Article
    Říhová, Blanka - Etrych, Tomáš - Šírová, Milada - Kovář, Lubomír - Hovorka, Ondřej - Kovář, Marek - Benda, Aleš - Ulbrich, Karel
    Synergistic action of doxorubicin bound to the polymeric carrier based on N-(2-hydroxypropyl)methacrylamide copolymers through and amide or hydrazone bond.
    Molecular Pharmaceutics. Roč. 7, č. 4 (2010), s. 1027-1040. ISSN 1543-8384. E-ISSN 1543-8392
    R&D Projects: GA AV ČR IAAX00500803; GA AV ČR IAA400500806; GA MŠMT 1M0505
    Institutional research plan: CEZ:AV0Z50200510; CEZ:AV0Z40500505; CEZ:AV0Z40400503
    Keywords : hpma * branched polymers * EL4 T cell lymphoma
    Subject RIV: EC - Immunology
    Impact factor: 5.400, year: 2010

    The cytostatic effects of polymeric conjugates based on N-(2-hydroxypropyl)methacrylamide copolymers (PHPMA) and containing doxorubicin bound through amide and hydrazone bonds (mixed conjugates) were compared with the cytostatic effects on monoconjugates containing drug bound through an amide or hydrazone bond
    Permanent Link: http://hdl.handle.net/11104/0006130

     
     
Number of the records: 1  

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