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Straightforward synthesis of 3´-deoxy-3´,4´-didehydronucleoside-5´-aldehydes via 2´,3´-O-orthoester group elimination: a simple route 3´,4´-didehydronucleosides

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    0350262 - ÚOCHB 2011 RIV GB eng J - Journal Article
    Petrová, Magdalena - Buděšínský, Miloš - Rosenberg, Ivan
    Straightforward synthesis of 3´-deoxy-3´,4´-didehydronucleoside-5´-aldehydes via 2´,3´-O-orthoester group elimination: a simple route 3´,4´-didehydronucleosides.
    Tetrahedron Letters. Roč. 51, č. 52 (2010), s. 6874-6876. ISSN 0040-4039. E-ISSN 1873-3581
    R&D Projects: GA ČR GA203/09/0820; GA MŠMT(CZ) LC06077; GA AV ČR KAN200520801
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : Moffat oxidation * beta-elimination * nucleoside-5'-aldehydes * 3',4'-didehydronucleosides
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.618, year: 2010

    Straightforward, high-yielding syntheses of 3´-deoxy-3´,4´-didehydronucleoside-5´-aldehydes and 3´-deoxy-3´,4´-didehydronucleosides starting from 2´,3´-orthoester derivatives of ribonucleosides are described.
    Permanent Link: http://hdl.handle.net/11104/0190305

     
     
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