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Surface plasmon resonance sensor with dispersionless microfluidics for direct detection of nucleic acids at the low femtomole level
- 1.0350250 - ÚFE 2011 RIV CH eng J - Journal Article
Špringer, Tomáš - Piliarik, Marek - Homola, Jiří
Surface plasmon resonance sensor with dispersionless microfluidics for direct detection of nucleic acids at the low femtomole level.
Sensors and Actuators B - Chemical. Roč. 145, č. 1 (2010), s. 588-591. E-ISSN 0925-4005
R&D Projects: GA AV ČR KAN200670701
Institutional research plan: CEZ:AV0Z20670512
Keywords : microfluidics * surface plasmon resonance * DNA detection
Subject RIV: JB - Sensors, Measurment, Regulation
Impact factor: 3.368, year: 2010
In the article we report on a surface plasmon resonance (SPR) sensor which incorporates novel microfluidics that delivers a sample to the sensing area without dispersion of the sample and thus enables faster and more sensitive detection. It is demonstrated that the sensor is able to detect short sequence of nucleic acids (20 bases) characteristic for Escherichia coli down to femtomole level in 4 min.
Permanent Link: http://hdl.handle.net/11104/0190296
Number of the records: 1