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Harmaline-resistant mutant of Methanothermobacter thermautotrophicus with a lesion in Na+/H +antiport
- 1.0349739 - ÚIACH 2012 RIV SK eng J - Journal Article
Vidová, M. - Bobálová, Janette - Šmigáň, P.
Harmaline-resistant mutant of Methanothermobacter thermautotrophicus with a lesion in Na+/H +antiport.
General Physiology and Biophysics. Roč. 30, SI (2011), S54-S60. ISSN 0231-5882. E-ISSN 1338-4325
Institutional research plan: CEZ:AV0Z40310501
Keywords : methanogens * harmaline resistance * sodium/proton exchange
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 1.192, year: 2011
A spontaneous mutant of Methanothermobacter thermautotrophicus resistant to the Na+/H+ antiporter inhibitor harmaline was isolated. The Na+/H+ exchange activity in the mutant cells was remarkably decreased in comparison with wild-type cells. Na+/H+ antiport activity of wild-type cells grown in the high Na+ concentration (125 mmol.l-1) was significantly increased as compared to the cells grown under low Na+ concentration (6.25 mmol.l-1) conditions.
Permanent Link: http://hdl.handle.net/11104/0189896
Number of the records: 1