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Extracellular cAMP inhibits P2X(3) receptors in rat sensory neurones through G protein-mediated mechanism
- 1.0349467 - ÚEM 2011 RIV US eng J - Journal Article
Mamenko, M. V. - Chizhmakov, I. V. - Volkova, T. M. - Verkhratsky, Alexei - Krishtal, O. A.
Extracellular cAMP inhibits P2X(3) receptors in rat sensory neurones through G protein-mediated mechanism.
Acta Physiologica. Roč. 199, č. 2 (2010), s. 199-204. ISSN 1748-1708. E-ISSN 1748-1716
Institutional research plan: CEZ:AV0Z50390703
Keywords : ATP * cAMP * cAMP receptors
Subject RIV: FH - Neurology
Impact factor: 3.138, year: 2010
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0349467_01.pdf
In this work, we demonstrate, for the first time, that extracellular application of cAMP to rat sensory neurones inhibits P2X(3) receptors via a G protein-coupled mechanism in a use-dependent manner, thus indicating the neuronal expression of specific plasmalemmal cAMP receptor.
Permanent Link: http://hdl.handle.net/11104/0189700
Number of the records: 1