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Cycloolefin-Copolymer/Polyethylene (COC/PE) Blend Assists with the Creation of New Articular Cartilage
- 1.0349339 - ÚFCH JH 2011 RIV DE eng J - Journal Article
Petrtýl, M. - Bastl, Zdeněk - Kruliš, Zdeněk - Hulejová, H. - Polanská, M. - Lísal, J. - Danešová, J. - Černý, P.
Cycloolefin-Copolymer/Polyethylene (COC/PE) Blend Assists with the Creation of New Articular Cartilage.
Macromolecular Symposia. 294-I, - (2010), s. 120-132. ISSN 1022-1360
R&D Projects: GA ČR GA106/06/0761
Institutional research plan: CEZ:AV0Z40400503; CEZ:AV0Z40500505
Keywords : articular cartilage * biomaterials * cycloolefin-copolymer blend
Subject RIV: CF - Physical ; Theoretical Chemistry
It is shown that the initial biomechanical stability of the applied COC/PE blend in the treated tissue locality, the initial integrity of biomaterials substituting the subchondral bone by polymer implant, the initial bearing capacity and the vertical position of these biomaterials have a mayor influence on the regeneration of new articular cartilage and subchondral bone. These aspects are essential for a prosperous treatment of osteochondral defects. Results reveal that the initial biomechanical stiffness of materials (substituting the subchondral bone) has a fundamental influence on both the quality and the quantity of new articular cartilage and subchondral bone. Research is also aimed at the application of suitable biologically tolerated polymer material, its surface modifications, verifications of the vertical position of implants in relation to the articular cartilage surface and ensuring the initial biomechanical stability of the polymer implant.
Permanent Link: http://hdl.handle.net/11104/0189605
Number of the records: 1