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Cell death/proliferation and alterations in glial morphology contribute to changes in diffusivity in the rat hippocampus after hypoxia-ischemia

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    0349045 - ÚEM 2011 RIV US eng J - Journal Article
    Anděrová, Miroslava - Voříšek, Ivan - Pivoňková, Helena - Benešová, Jana - Vargová, Lýdia - Cicanič, Michal - Chvátal, Alexandr - Syková, Eva
    Cell death/proliferation and alterations in glial morphology contribute to changes in diffusivity in the rat hippocampus after hypoxia-ischemia.
    Journal of Cerebral Blood Flow and Metabolism. Roč. 31, č. 3 (2011), s. 894-907. ISSN 0271-678X. E-ISSN 1559-7016
    R&D Projects: GA ČR GA305/09/0717; GA ČR GA309/09/1597; GA MŠMT(CZ) LC554; GA ČR GAP303/10/1338
    Grant - others:MZd(CZ) MZ0IKEM2005
    Institutional research plan: CEZ:AV0Z50390512
    Keywords : astrocytes * extracellular volume * microglia
    Subject RIV: FH - Neurology
    Impact factor: 5.008, year: 2011

    In this work, we have demonstrated that hypoxia/ischemia-induced alterations in cell number, cell-type composition and glial morphology in the rat hippocampal CA1 region contribute significantly to the changes in apparent diffusion coeficient of water and extracellular space diffusion parameters during acute and late phases of reperfusion.
    Permanent Link: http://hdl.handle.net/11104/0007383

     
     
Number of the records: 1  

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