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Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and Nanofibres
- 1.0348754 - ÚŽFG 2011 RIV CZ eng J - Journal Article
Nečas, A. - Plánka, L. - Srnec, R. - Crha, M. - Hlučilová, Jana - Klíma, Jiří - Starý, L. - Křen, L. - Amler, Evžen - Vojtová, L. - Jančář, J. - Gál, P.
Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and Nanofibres.
Physiological Research. Roč. 59, č. 4 (2010), s. 605-614. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MŠMT 2B06130
Institutional research plan: CEZ:AV0Z50450515; CEZ:AV0Z50390512
Keywords : Cartilaginous Tissue * Defects of Articular Surface * Mesenchymal Stem Cells
Subject RIV: CE - Biochemistry
Impact factor: 1.646, year: 2010
The aim of this study was to evaluate macroscopically, histologically and immunohistochemically the quality of newly formed tissue in iatrogenic defects of articular cartilage of the femur condyle in miniature pigs treated with the clinically used method of microfractures in comparison with the transplantation of a combination of a composite scaffold with allogeneic mesenchymal stem cells (MSCs) or the composite scaffold alone.
Permanent Link: http://hdl.handle.net/11104/0189191
Number of the records: 1