Study of rheological and electrical behaviour of RBC suspensions in dextran and PEG under non-steady flow. Role of RBC deformability and morphology

0348106 - ÚH 2011 RIV DE eng C - Conference Paper (international conference)
Antonova, N. - Říha, Pavel - Ivanov, I. - Gluhcheva, Y.
Study of rheological and electrical behaviour of RBC suspensions in dextran and PEG under non-steady flow. Role of RBC deformability and morphology.
6th World Congress of Biomechanics (WCB 2010). Heidelberg: Springer, 2010 - (Lim, C.; Goh, J.), s. 330-333. IFMBE Proceedings, vol. 31. ISBN 978-3-642-14514-8. ISSN 1680-0737.
[WCB 2010: World Congress of Biomechanics /6./. Singapore (SG), 01.08.2010-06.08.2010]
R&D Projects: GA AV ČR IAA200600803
Institutional research plan: CEZ:AV0Z20600510
Keywords : electrorheology * RBC suspensions in dextrans and PEG solutions * conductivity * deformability * RBC morphology
Subject RIV: BK - Fluid Dynamics
http://www.springerlink.com/content/h31423474480p417/

The electrical conductivity and shear rate dependences in parallel with the rheological properties of the samples were studied under transient flow regimes at different local structure of the uniform Couette flow. Red blood cells (RBC) were treated with glutaraldehyde (GA) with different concentrations (from 0,01% to 1%). A time course of conductivity of normal RBC and treated with GA suspended in dextran 70 was recorded under trapezoid change of shear rates. It provides experimental description of RBC aggregation-disaggregation processes and other cell-cell interactions. Dextrans induce morphological alterations in RBC shape and arrangement in the suspensions. Echinocytes are observed at low Dx 70 concentrations while spherocytes are found mainly in smears at higher Dx 70 concentrations. Their morphological characteristics affect blood electrical and mechanical properties.
Permanent Link: http://hdl.handle.net/11104/0188719