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Modulation of type I iodothyronine 5’-deiodinase activity in white adipose tissue by nutrition: possible involvement of leptin
- 1.0347895 - FGÚ 2011 RIV CZ eng J - Journal Article
Macek Jílková, Zuzana - Pavelka, Stanislav - Flachs, Pavel - Hensler, Michal - Kůs, Vladimír - Kopecký, Jan
Modulation of type I iodothyronine 5’-deiodinase activity in white adipose tissue by nutrition: possible involvement of leptin.
Physiological Research. Roč. 59, č. 4 (2010), s. 561-569. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GD305/08/H037; GA MŠMT(CZ) OC08007
Institutional research plan: CEZ:AV0Z50110509
Keywords : adipose tissue * thyroid hormones * obesity
Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition
Impact factor: 1.646, year: 2010
Our objective was to describe possible changes in activities of TH-metabolizing enzymes in white adipose tissue, and the role of TH metabolism in the tissue during obesogenic treatment, caloric restriction and in response to leptin in mice. Our results suggest a functional role for D1 in white adipose tissue, with D1 possibly being involved in the control of adipose tissue metabolism and/or accumulation of the tissue
Permanent Link: http://hdl.handle.net/11104/0188565
Number of the records: 1