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Genetic variants in selenoprotein genes increase risk of colorectal cancer
- 1.0347494 - ÚEM 2011 RIV GB eng J - Journal Article
Méplan, C. - Hughes, D. J. - Pardini, Barbara - Naccarati, Alessio - Souček, P. - Vodičková, Ludmila - Hlavatá, I. - Vrána, D. - Vodička, Pavel - Hesketh, J. E.
Genetic variants in selenoprotein genes increase risk of colorectal cancer.
Carcinogenesis. Roč. 31, č. 6 (2010), s. 1074-1079. ISSN 0143-3334. E-ISSN 1460-2180
R&D Projects: GA ČR(CZ) GA310/07/1430; GA ČR GP305/09/P194
Grant - others:EU(XE) FP6-505360
Institutional research plan: CEZ:AV0Z50390512
Keywords : colorectal cancer * Selenium
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.402, year: 2010
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0347494_01.pdf
This study analysed 12 single-nucleotide polymorphisms (SNPs) in selenoprotein genes and in genes that code for a key protein in Se incorporation in relation to sporadic CRC incidence. The results indicate that SNPs in SEPP1, GPX4 and SELS influence risk of CRC.
Permanent Link: http://hdl.handle.net/11104/0188266
Number of the records: 1