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Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats
- 1.0347398 - ÚOCHB 2011 RIV US eng J - Journal Article
Straková, J. - Williams, K. T. - Gupta, S. - Schalinske, K. L. - Kruger, W. D. - Rozen, R. - Jiráček, Jiří - Li, L. - Garrow, T. A.
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
Nutrition Research. Roč. 30, č. 7 (2010), s. 492-500. ISSN 0271-5317. E-ISSN 1879-0739
R&D Projects: GA ČR(CZ) GAP207/10/1277
Grant - others:NIH(US) DK52501
Institutional research plan: CEZ:AV0Z40550506
Keywords : BHMT * homocysteine * rat * betaine
Subject RIV: CC - Organic Chemistry
Impact factor: 2.092, year: 2010
In the present study, CBHcy, an inhibitor of BHMT enzyme was fed to rats. CBHcy-mediated BHMT inhibition causes an elevation in total plasma Hcy that is not normalized by the folate-dependent conversion of Hcy to methionine. methionine.
Permanent Link: http://hdl.handle.net/11104/0188184
Number of the records: 1