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Phenotyping breast cancer cell lines EM-G3, HCC1937, MCF7 and MDA-MB-231 using 2-D electrophoresis and affinity chromatography for glutathione-binding proteins

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    0347194 - ÚOCHB 2011 RIV GB eng J - Journal Article
    Mládková, Jana - Šanda, Miloslav - Matoušková, E. - Selicharová, Irena
    Phenotyping breast cancer cell lines EM-G3, HCC1937, MCF7 and MDA-MB-231 using 2-D electrophoresis and affinity chromatography for glutathione-binding proteins.
    Bmc Cancer. Roč. 10, - (2010), 449/1-449/10. E-ISSN 1471-2407
    R&D Projects: GA MŠMT(CZ) LC06077
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : 2-DE * breast cancer * glutathione
    Subject RIV: CC - Organic Chemistry
    Impact factor: 3.153, year: 2010
    http://www.biomedcentral.com/1471-2407/10/449

    Transformed phenotypes are common to cell lines derived from various cancers. We performed proteome profiling of breast cancer cell lines EM-G3, HCC1937, MCF7 and MDA-MB-231using 2-DE in combination with affinity chromatography for GSH-binding proteins. Major differences in expression of enzymes metabolizing xenobiotics were observed among the cell lines.
    Permanent Link: http://hdl.handle.net/11104/0188026

     
     
Number of the records: 1  

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