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TGF-beta1 suppresses IL-6-induced STAT3 activation through regulation of Jak2 expression in prostate epithelial cells
- 1.0347188 - BFÚ 2011 RIV US eng J - Journal Article
Staršíchová, Andrea - Lincová, Eva - Pernicová, Zuzana - Kozubík, Alois - Souček, Karel
TGF-beta1 suppresses IL-6-induced STAT3 activation through regulation of Jak2 expression in prostate epithelial cells.
Cellular Signalling. Roč. 22, č. 11 (2010), s. 1734-1744. ISSN 0898-6568. E-ISSN 1873-3913
R&D Projects: GA MZd NS9600
Grant - others:GA ČR(CZ) GA310/07/0961
Program: GA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : interleukin-6 * transforming growth factor-beta * prostate
Subject RIV: BO - Biophysics
Impact factor: 4.243, year: 2010
Our study demonstrated a novel interaction between TGF-beta1 and IL-6 signalling and suggested another mechanism of how defects in TGF-beta signalling, frequently associated with prostate pathologies, can contribute to the disruption of tissue homeostasis.
Permanent Link: http://hdl.handle.net/11104/0188020
Number of the records: 1