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Spatio-temporal changes of SDF1 and its CXCR4 receptor in the dorsal root ganglia following unilateral sciatic nerve injury as a model of neuropathic pain

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    0347087 - BFÚ 2011 RIV US eng J - Journal Article
    Dubový, P. - Klusáková, I. - Svíženská, I. - Brázda, Václav
    Spatio-temporal changes of SDF1 and its CXCR4 receptor in the dorsal root ganglia following unilateral sciatic nerve injury as a model of neuropathic pain.
    Histochemistry and Cell Biology. Roč. 133, č. 3 (2010), s. 323-337. ISSN 0948-6143. E-ISSN 1432-119X
    Grant - others:GA ČR(CZ) GA309/07/0121
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : chemokine * satellite glial cells * chronic constriction injury
    Subject RIV: BO - Biophysics
    Impact factor: 4.727, year: 2010

    There is a growing evidence that chemokines and their receptors play a role in inducing and maintaining neuropathic pain. In the present study, unilateral chronic constriction injury (CCI) of rat sciatic nerve was used to investigate changes for stromal derived factor-1 (SDF1) and its CXCR4 receptor in lumbal and cervical dorsal root ganglia from both sides of naive, operated and sham-operated rats.
    Permanent Link: http://hdl.handle.net/11104/0187944

     
     
Number of the records: 1  

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