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Natural variation explains most transcriptomic changes among maize plants of MON810 and comparable non-GM varieties subjected to two N-fertilization farming practices
- 1.0346926 - BTÚ 2011 RIV US eng J - Journal Article
Coll, A. - Nadal, A. - Collado, R. - Capellades, G. - Kubista, Mikael - Messeguer, J. - Pla, M.
Natural variation explains most transcriptomic changes among maize plants of MON810 and comparable non-GM varieties subjected to two N-fertilization farming practices.
Plant Molecular Biology. Roč. 73, č. 3 (2010), s. 349-362. ISSN 0167-4412. E-ISSN 1573-5028
Institutional research plan: CEZ:AV0Z50520701
Keywords : GMO (Genetically Modified Organism) * MON810 * Maize * Transcriptome
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.149, year: 2010
Over the last few years, targeted approaches have been complemented by profiling methods to assess possible unintended effects of transformation of GMO. Here we used Affymetrix microarray platform to evaluate transcriptional differences between commercial MON810 GM maize and non-transgenic crops. We took two common MON810/non-GM variety pairs and two farming practices. MON810 and comparable non-GM varieties have very low numbers of sequences with differential expression. We show, the differences between a given MON810 variety and the non-GM do not depend on the assayed cultural conditions. Natural variation explained most of the variability in gene expression. Up to 37 % was dependent upon the variety and 32 % a result of the fertilization. The MON810 had minor effect (9.7%) on gene expression. This indicates that transcriptional differences of conventionally-bred varieties and different environmental conditions should be taken into account in safety assessment studies of GM plants.
Permanent Link: http://hdl.handle.net/11104/0187826
Number of the records: 1