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Growth/differentiation factor-15 inhibits differentiation into osteoclasts - A novel factor involved in control of osteoclast differentiation
- 1.0345304 - BFÚ 2011 RIV DE eng J - Journal Article
Vaňhara, P. - Lincová, Eva - Kozubík, Alois - Jurdic, P. - Souček, Karel - Šmarda, J.
Growth/differentiation factor-15 inhibits differentiation into osteoclasts - A novel factor involved in control of osteoclast differentiation.
Differentiation. Roč. 78, č. 4 (2009), s. 213-222. ISSN 0301-4681. E-ISSN 1432-0436
R&D Projects: GA ČR(CZ) GA204/07/0834
Grant - others:GA ČR(CZ) GA301/06/0036; GA ČR(CZ) GD204/08/H054; GA ČR(CZ) GA310/07/0961
Program: GA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : osteoclast differentiation * GDF-15 * prostate cancer
Subject RIV: BO - Biophysics
Impact factor: 3.311, year: 2009
Both purified GDF-15 and unpurified product secreted by prostate cancer cells strongly intereferes with differentiation of osteoclasts by inhibiting expression and activity of NFkappaB and c-Fos transcription factors.
Permanent Link: http://hdl.handle.net/11104/0186612
Number of the records: 1