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A label-free electrochemical test for DNA-binding activities of tumor suppressor protein p53 using immunoprecipitation at magnetic beads

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    0345100 - BFÚ 2011 RIV NL eng J - Journal Article
    Němcová, Kateřina - Havran, Luděk - Šebest, Peter - Brázdová, Marie - Pivoňková, Hana - Fojta, Miroslav
    A label-free electrochemical test for DNA-binding activities of tumor suppressor protein p53 using immunoprecipitation at magnetic beads.
    Analytica Chimica Acta. Roč. 668, č. 2 (2010), s. 166-170. ISSN 0003-2670. E-ISSN 1873-4324
    R&D Projects: GA AV ČR(CZ) IAA500040701; GA ČR(CZ) GP204/07/P476; GA ČR(CZ) GA204/08/1560; GA AV ČR(CZ) 1QS500040581; GA MŠMT(CZ) LC06035
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : electrochemical analysis * label-free detection * tumor suppressor protein p53
    Subject RIV: BO - Biophysics
    Impact factor: 4.310, year: 2010

    We extend the application area of the label-free structure selective electrochemical DNA sensing with mercury based electrodes which is for the first time used, in combination with immunoprecipitation at magnetic beads, for the probing of DNA interactions with tumor suppressor protein p53.
    Permanent Link: http://hdl.handle.net/11104/0186445

     
     
Number of the records: 1  

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