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SUV39h-independent association of HP1beta with fibrillarin-positive nucleolar regions

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    0343809 - BFÚ 2011 RIV DE eng J - Journal Article
    Harničarová, Andrea - Bártová, Eva - Galiová-Šustáčková, Gabriela - Uhlířová, Radka - Matula, P. - Kozubek, Stanislav
    SUV39h-independent association of HP1beta with fibrillarin-positive nucleolar regions.
    Chromosoma. Roč. 119, č. 3 (2010), s. 227-241. ISSN 0009-5915. E-ISSN 1432-0886
    R&D Projects: GA MŠMT ME 919; GA AV ČR(CZ) 1QS500040508
    Grant - others:GA MŠk(CZ) LC06027; GA MŠk(CZ) LC535; GA MŠk(CZ) 2B06052
    Program: LC; LC
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : SUV39h * histone methyltransferases * chromatin structure
    Subject RIV: BO - Biophysics
    Impact factor: 4.196, year: 2010

    Deficiency of histone methyltransferase SUV39h, and/or inhibition of histone deacetylases (HDACi) decreased HP1beta and H3K9 trimethylation at chromocenters, but not in fibrillarin-positive regions that co-localized with RNA Pol I. Similarly, SUV39h- and HDACi-dependent nucleolar rearrangement and inhibition of rDNA transcription did not affect the stability of the HP1beta-fibrillarin.
    Permanent Link: http://hdl.handle.net/11104/0186198

     
     
Number of the records: 1  

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